| Date | Location | Result | |
| Nov 13, 2021 | Athens, W.Va. | Concord 28, UNC Pembroke 25 | Box score |
| Nov 06, 2021 | Pembroke, N.C. | Notre Dame (Ohio) 45, UNC Pembroke 7 | Box score |
| Oct 30, 2021 | West Liberty, W.Va. | UNC Pembroke 27, West Liberty 17 | Box score |
| Oct 23, 2021 | Pembroke, N.C. | UNC Pembroke 21, Charleston (W.Va.) 14 | Box score |
| Oct 16, 2021 | Institute, WV | UNC Pembroke 14, West Virginia St. 13 | Box score |
| Oct 09, 2021 | Pembroke, N.C. | UNC Pembroke 34, Wheeling 28 | Box score |
| Oct 02, 2021 | Frostburg, Maryland | Frostburg St. 51, UNC Pembroke 21 | Box score |
| Sep 25, 2021 | Pembroke, N.C. | Fairmont State 30, UNC Pembroke 27 | Box score |
| Sep 18, 2021 | Pembroke, N.C. | UNC Pembroke 36, Glenville State 22 | Box score |
| Sep 11, 2021 | Findlay, Ohio | Findlay 34, UNC Pembroke 28 | Box score |